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Nathalie PICARD

CAMBRIDGE

En résumé

My research interests are to understand how neuronal circuits are established during development and how disturbances, linked to genetic mutations or caused by environmental inputs, can produce disorders. To further understand these processes, I have chosen to combine multidisciplinary methods, from in vivo studies (behavioral tests and in vivo electrophysiology) to cellular and molecular analysis (immunohistochemistry, qPCR and Western Blot).

Mes compétences :
Data analysis (statistics, matlab)
In vivo electrophysiology
Behavior tests
Immunohistochemistry
In vitro electrophysiology
Molecular analysis
Student training
Communication
Design and management of research projects

Entreprises

  • Boston Childrens Hospital- Harvard Medical School - Research Fellow

    2009 - maintenant Study of mechanisms involved in visual cortex maturation and experience-dependent development in mouse
    models of Rett syndrome and Autism Spectrum Disorders.
    - Designed and managed research projects (2 main projects and 3 projects in collaboration). ;
    - Supervised and Trained students (1 Undergraduate for 6 months and 3 PhD students-3 to 6 months). ;
    - Developed/set-up the plethysmographic system for the IDDRC-Neurodevelopmental Behavior Core. ;
    - Created new Matlab programs to analyze single-unit/VEP recordings. ;
    - Developed/tested a treatment in mouse model of Rett syndrome.

  • CNRS - Postdoctoral Research Fellow

    Paris 2008 - 2009 University Paul Sabatier, CNRS, Brain and Cognition Research Center - Toulouse, France
    Role of feedback connections from area MT to V1 in the two prime features of cortical visual processing in the
    marmoset monkey: control of contrast response function and the center-surround interaction.
    - Contributed to improve surgical procedures to obtain relevant and reproducible experiments. ;
    - Managed data analysis/processing.

  • University Paul Cezanne - PhD Student

    2003 - 2007 University Paul Cezanne, CNRS, Neurobiology and Neurophysiology Research Center - Marseille, France
    University Picardie Jules Verne, Laboratory of metabolic and genetic deregulations - Amiens, France
    Multidisciplinary study of psychoactive drugs exposure (diazepam and caffeine) on breathing control in newborn
    rats.
    - Designed and managed the project. ;
    - Responsible for reporting with the French Council of Picardie and EU Fund funding the project. ;
    - Adapted and standardized methods to small animals. ;
    - Developed and designed real-time RT-PCR technique in collaboration with C2RBM and UTC.

  • Pierre Fabre - Master Trainee

    Castres 2003 - 2003 Pierre Fabre research Center, Division of General Pharmacology-
    Pharmacological study of compounds in pain related field.
    - Performed behavioral tests under the supervision of senior scientists.

Formations

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